Which A/B classification is an augmented pharmacologic effect that is dose dependent and predictable?

Which A/B classification is an augmented pharmacologic effect that is dose dependent and predictable?

• A. Type A
• B. Type B
• C. Type D
• D. Type C

Answer: (A)

Understanding how adverse drug reactions are categorized by predictability and dose dependence helps explain this item. Augmented reactions are increases in the drug’s pharmacologic effect that occur in a dose-dependent, predictable manner, tied to the drug’s known action. Because the description specifies an augmented pharmacologic effect that is dose dependent and predictable, this fits Type A best. Bizarre reactions are unpredictable and not dose-related; chronic reactions stem from long-term use; delayed reactions occur after a latent period rather than directly scaling with dose.

Understanding how adverse drug reactions are categorized by predictability and dose dependence helps explain this item. Augmented reactions are increases in the drug’s pharmacologic effect that occur in a dose-dependent, predictable manner, tied to the drug’s known action. Because the description specifies an augmented pharmacologic effect that is dose dependent and predictable, this fits Type A best. Bizarre reactions are unpredictable and not dose-related; chronic reactions stem from long-term use; delayed reactions occur after a latent period rather than directly scaling with dose.